Session 1
Protein Homeostasis & Neural Diseases
9:00-9:10 Opening Remarks
9:10-9:40
Dr.Franz-Ulrich Hartl
Max Planck Institute of Biochemistry, Germany
Molecular chaperones ¨C cellular machineries of protein folding and proteostasis
9:40-10:10
Dr.Kazutoshi Mori
University of Kyoto, Japan
A Motor Neuron Disease-associated Mutation Produces Non-glycosylated Seipin that Induces ER Stress and Apoptosis by Inactivating SERCA2b
10:40-11:10
Dr.Manajit Hayer-Hartl
Max Planck Institute of Biochemistry, Germany
Multiple protein interactions mediate the biogenesis of a bacterial microcompartment
11:10-11:40
Dr. Rui Zhou
Tsinghua University, China
Structural Mechanism of ¦Ã-secretase Cleavage and Regulation: Towards Understanding the Molecular Basis of Alzheimer¡¯s Disease
11:40-12:10
Dr.Anne Bertolotti
MRC Laboratory of Molecular Biology, U.K
Therapeutic manipulations of protein quality control systems: From the bench, to the clinic
Session 2
Sleep and Circadian Rhythm Related Disorders
13:30-14:00
Dr.Joseph Takahashi
University of Texas Southwestern Medical Center, U.S.A.
Circadian Clocks and Their Impact on Metabolism, Aging and Longevity
14:00-14:30
Dr.Donggen Luo
Peking University, China
A single photoreceptor splits perception and photoentrainment via cotransmission
14:30-15:00
Dr.Erquan Zhang
National Institute of Biological Sciences, China
Prolonged sleep deprivation induces a cytokine storm-like syndrome in mammals
15:30-16:00
Dr.Qinghua Liu
National Institute of Biological Sciences, China
Towards the mystery of sleep¨CHow is sleep amount regulated£¿
16:00-16:30
Dr.Takeshi Sakuri
International Institute for Integrative Sleep Medicine, U of Tsukuba, Japan
Connecting the Amygdala and Dopamine: Exploring the Mechanism of REM Sleep
16:30-17:00
Dr.Yi Lin
Tsinghua University, China
Circadian clocks are modulated by compartmentalized oscillating translation
Session 3
Molecular Mechanisms of Neurodegeneration
9:00-9:30
Dr.Aaron Gitler
Stanford University, U.S.A
Expanding mechanisms and therapeutic targets for neurodegenerative disease
9:30-10:00
Dr.Ge Bai
Zhejiang University, China
Stress granule and neurodegeneration
10:00-10:30
Dr.Cong Liu
Interdisciplinary Research Center on Biology and Chemistry, CAS, China
Mechanistic Basis of Pathological Protein Aggregation in Parkinson's Disease
10:50-11:20
Dr.Yichang Jia
Tsinghua University, China
From rational ALS animal models to ALS therapy
11:20-11:50
Dr.Kirsty McMillan
University of Bristol, U.K
Endo-lysosomal Trafficking Dysfunction: A Roadmap to Neurodegenerative Disease?
Session 4
Therapies for Neurodegenerative Diseases
13:30-14:00
Dr.Junying Yuan
Interdisciplinary Research Center on Biology and Chemistry, CAS, China
RIPK1-mediated inflammatory response and neurological diseases
14:00-14:30
Dr.Yi Zhong
Tsinghua University, China
Studying Alzheimer¡¯s disease on convergent point of disease pathology
14:30-15:00
Dr.Boxun Lu
Fudan University, China
Targeting Misfolded Proteins in Neurodegenerative Disorders by Small Molecule Compounds
15:30-16:00
Dr.Bai Lu
Tsinghua University, China
Novel strategies for the treatment of neurodegenerative diseases
16:00-16:30
Dr.Wenkai Li
Biogen, China
Neuroscience Drug Discovery and Development ¨C Current Challenges and Mitigation Strategies
16:30-17:00
Dr.Dongsheng Fan
Peking University Third Hospital, China
Cognitive and Behavioural impairment in ALS
17:00-17:30
Dr.Gong Chen
Jinan University, China
Neural Regenerative Gene Therapy to Treat Degenerative Disorders
17:30-17:35 Closing Remarks
Source: IDG/MCGOVERN Institute For Brain Research Institute at Tsinghua
